The rules for this game are simple: Each contestant admits something they've never done. For example, "I never went to a bar without underwear." Anyone who has ever left the house to do a little cruising commando has to drink. You are perfectly free to say you've never done something that you actually have -- as long as you drink anyway. Hilarity will be the order of the evening as everyone watches who is taking a drink.
The key to this game is creativity. Think of the most bizarre things you've never -- or ever -- done. You may learn more about each other than you ever wanted to know, which is the whole point of this game.
Celebrity Games
This is a great game with a lot of variations to it. Pick any genre (actors, TV personalities, or people you actually know). Then pick a category like "people ever slept with" or, in the case of actors, "participation in movies that bombed."
Here's another example. You name a musician; the next player has to name a song. Others continue to name songs until you've exhausted the musician's catalog of recordings. Or name an oft-recorded song and try to name everyone who has recorded it. Name all the musicians who died of drug- or alcohol-related causes. Pick a letter of the alphabet and name as many musicians as you can whose name starts with that letter. Whoever gets stumped, of course, drinks.
The Hour of Power
A note of warning: This game is geared toward guests who can hold their liquor. Guests drink a shot of beer every minute or two for an hour (adjust the time accordingly for your particular group). An alternative is to substitute hard liquor every 15 minutes.
Alphabet Games
There are two popular versions of stumping people with letters. The first is to pick a genre broad enough so that there are actually enough items in the genre to begin with every letter of the alphabet -- geography is popular. Have everyone take turns naming an item in the genre, going in alphabetic order -- Albany, Buffalo, Cleveland, and so on. At the end of the alphabet, start over. Whoever stops the alphabet train has to take a drink.
Another version of this game is to choose a genre and then each person has to come up with an answer that starts with the last letter of the previous answer. So, starting again with Albany, the next answer would have to start with Y -- Ypsilanti, for example. And then the next answer would start with I. This game is a little trickier, especially after a few drinks.
Horror Shows
If you're married, pull out your wedding video. If not, ask a married friend to bring hers. Every time the camera shows the bride's fake, nervous smile, everyone drinks. Or drink every time the hyperventilating groom wipes his brow, every time a drunken bridesmaid stumbles across the dance floor, every time one of the wedding guests calls the bride or the groom by the wrong name while wishing them well, etc.
A great alternative is to pull out an old prom video, if you have one. Set your own rules and keep the wine flowing. It could be a painful show.
Many bachelorette parties have adult themes, with X-rated foods, male strippers, and even racy games. There is an abundance of paraphernalia available -- enough to host a party every night for a week without repeating your games or decorations.

